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A method for glycoconjugate synthesis
Authors:Vince Pozsgay
Institution:(1) Laboratory of Molecular and Developmental Immunity, National Institute of Child Health and Human Development, Bldg 6, Rm 145, 20892 Bethesda, MD, USA;(2) Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bldg 6, Rm 145, 20892 Bethesda, MD, USA;(3) Department of Biochemistry and Complex Carbohydrate Research Center, University of Georgia, Athens, GA, USA
Abstract:7-Formylheptyl glycosides of 2-acetamido-2-deoxy-beta-d-glucopyranose andO-agr-l-rhamnopyranosyl-(1 rarr 3)-O-agr-l-rhamnopyranose were synthesized and were coupled by reductive amination to bovine serum albumin and aminopropyl glass, respectively.
Keywords:glycoconjugate synthesis  reductive amination  ohgr-aldehydoalkyl aglycon" target="_blank">gif" alt="ohgr" align="BASELINE" BORDER="0">-aldehydoalkyl aglycon  immunoadsorbent  disaccharide
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