Red cell phospholipids in schizophrenia |
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| Authors: | Andrew Lautin Donna Mandio Cordasco David J. Segarnick Lawrence Wood Michael F. Mason Adam Wolkin John Rotrosen |
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| Affiliation: | 1. Psychiatry Service New York Veterans Administration Medical Center First Ave. and E. 24th Street New York, NY 10010, USA;2. Department of Psychiatry New York University School of Medicine 550 First Avenue New York, NY 10016, USA |
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| Abstract: | Phospholipids in red blood cells (RBCs) of schizophrenics and controls were determined. Three different RBC preparations and two different extraction methods were used. Phospholipids were separated by thin layer chromatography and by high pressure liquid chromatography, and were quantified by phosphorus analysis and by ultraviolet absorption. Findings were consistent with values previously reported for normals. However, in contrast to recent reports of elevated phosphatidylserine levels in schizophrenics' RBCs, we observed no differences between populations. |
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