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Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis
Authors:Sudhir Chowdhry  Maiiada H. Nazmy  Paul J. Meakin  Albena T. Dinkova-Kostova  Shaun V. Walsh  Tadayuki Tsujita  John F. Dillon  Michael L.J. Ashford  John D. Hayes
Affiliation:1. Biomedical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK;2. Department of Medicine and Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD 21205, USA;3. Department of Pathology, Ninewells Hospital, Tayside NHS Trust, Dundee DD1 9SY, Scotland, UK;3. From the Department of Experimental Pathology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan,;4. Center for Tsukuba Advanced Research Alliance, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Japan,;5. Department of Stress Response Science, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan,;6. Center for Radioisotope Sciences and;12. Medical Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan, and;8. Department of Molecular Pathology, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan;1. Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, RI 02881, USA;2. Pathology and Laboratory Medicine, Providence VA Medical Center, Providence, RI 02908, USA;3. Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI 48824, USA;4. Division of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan;1. Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD, USA;2. Department of Pharmacology & Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA;3. The Center for Metabolism and Obesity Research, School of Medicine, The Johns Hopkins University, Baltimore, MD, USA;4. Department of Medical Biochemistry, Graduate School of Medicine, Tohoku University, Sendai, Japan;5. Department of Environmental Health Sciences, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD, USA;1. Department of Endocrinology, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China;2. Department of Pharmacy, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China;3. School of Pharmacy, Weifang Medical University, Weifang, 261031, China;4. Department of Pathology, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China;1. Program of Environmental Toxicology, School of Public Health, China Medical University, Shenyang, Liaoning, 110122, PR China;2. Program of Chronic Disease and Environmental Genomics, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning, 110122, PR China
Abstract:
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