Synthesis and evaluation of 5-HT(2A) and 5-HT(2C) receptor binding affinities of novel pyrimidine derivatives |
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Authors: | Bózsing Dániel Simonek Ildikó Simig Gyula Jakóczi Iván Gacsályi István Lévay György Tihanyi Károly Schmidt Eva |
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Affiliation: | Chemical Research Department, EGIS Pharmaceuticals Ltd., PO Box 100, 1475, Budapest, Hungary. chemistry.rd@egis.hu |
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Abstract: | In an effort to find potential anxiolytic and/or antipsychotic agents with selective 5-HT(2C) affinity a series of new pyrimidine derivatives was prepared and the binding affinities for 5-HT(2A) and 5-HT(2C) receptors were determined. |
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