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Synthesis and evaluation of 5-HT(2A) and 5-HT(2C) receptor binding affinities of novel pyrimidine derivatives
Authors:Bózsing Dániel  Simonek Ildikó  Simig Gyula  Jakóczi Iván  Gacsályi István  Lévay György  Tihanyi Károly  Schmidt Eva
Affiliation:Chemical Research Department, EGIS Pharmaceuticals Ltd., PO Box 100, 1475, Budapest, Hungary. chemistry.rd@egis.hu
Abstract:
In an effort to find potential anxiolytic and/or antipsychotic agents with selective 5-HT(2C) affinity a series of new pyrimidine derivatives was prepared and the binding affinities for 5-HT(2A) and 5-HT(2C) receptors were determined.
Keywords:
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