The effect of pregnant mare serum gonadotropin on mouse oocytes as monitored at metaphase II |
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Authors: | Gray M H Chrisman C L |
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Affiliation: | Department of Animal Sciences, Purdue University West Lafayette, IN 47907 USA. |
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Abstract: | Ovulated oocytes were collected from random-bred, 7-12 week old ICR mice injected with 0, 3, or 6 i.u. pregnant mare serum gonadotropin (PMSG). Analyses of 872 metaphase figures from 87 females did not show a significant increase in chromosomal imbalance with PMSG treatment. A tendency toward ovum fragmentation was noted with an increase in PMSG dose. |
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