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Nucleotide sequence of a cDNA clone for human aldolase B
Authors:C Besmond  J C Dreyfus  C Gregori  M Frain  M M Zakin  J Sala Trepat  A Kahn
Institution:1. Institut de Pathologie Moléculaire, INSERM U 129, Chu Cochin, 24 rue du Faubourg St Jacques, 75674 Paris Cedex 14 - France;2. Laboratoire d''Enzymologie du CNRS, 91110 Gif Sur Yvette - France;3. Unité de Biochimie Cellulaire, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15 - France
Abstract:Two specific clones for human aldolase B were isolated from a human liver cDNA library using a rat aldolase B cDNA probe. The clones were identified by positive hybridization-selection and one of them was sequenced. The 127 C-terminal residues of the human protein were deduced from this nucleotide sequence analysis. They showed 92% homology with the corresponding previously published amino-acid sequence of rat liver aldolase B.
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