Rapid C-carboxylation of nitro[(11)C]methane for the synthesis of ethyl nitro[2-(11)C]acetate |
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| Authors: | Kato Koichi Zhang Ming-Rong Suzuki Kazutoshi |
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| Institution: | Department of Molecular Probes, Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan. katok@nirs.go.jp |
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| Abstract: | The labelling synthesis of ethyl nitro2-(11)C]acetate, a synthetic intermediate feasible for (11)C-labelled PET tracers, by C-carboxylation of (11)C]MeNO(2) with 1-ethoxycarbonylbenzotriazole, and its simple application are presented. |
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