| 肠道菌群对糖脂代谢影响的研究进展 |
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| 引用本文： | 杨俊,王健宇,陈茏,周飞,曾哲灵,文学方.肠道菌群对糖脂代谢影响的研究进展[J].微生物学通报,2019,46(5):1146-1154. |
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| 作者姓名： | 杨俊 王健宇 陈茏 周飞 曾哲灵 文学方 |
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| 作者单位： | 1 南昌大学食品科学与技术国家重点实验室 江西 南昌 330047;2 南昌大学江西省药食同源植物资源高值化利用重点实验室 江西 南昌 330031;3 南昌大学食品学院 江西 南昌 330031,2 南昌大学江西省药食同源植物资源高值化利用重点实验室 江西 南昌 330031;4 南昌大学资源环境与化工学院 江西 南昌 330031,1 南昌大学食品科学与技术国家重点实验室 江西 南昌 330047;3 南昌大学食品学院 江西 南昌 330031,2 南昌大学江西省药食同源植物资源高值化利用重点实验室 江西 南昌 330031;4 南昌大学资源环境与化工学院 江西 南昌 330031,1 南昌大学食品科学与技术国家重点实验室 江西 南昌 330047;2 南昌大学江西省药食同源植物资源高值化利用重点实验室 江西 南昌 330031;4 南昌大学资源环境与化工学院 江西 南昌 330031,1 南昌大学食品科学与技术国家重点实验室 江西 南昌 330047;2 南昌大学江西省药食同源植物资源高值化利用重点实验室 江西 南昌 330031;4 南昌大学资源环境与化工学院 江西 南昌 330031 |
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| 基金项目： | 国家国际科技合作专项项目(2011DFA32770)；江西省国际科技合作项目(20112BDH80004，20123BDH80011)；食品科学及技术国家重点实验室目标导向项目(SKLF-ZZA-201303) |
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| 摘 要： | 目前越来越多的研究成果表明被誉为人类"第二基因组"的肠道菌群能够影响糖脂代谢,进而调节相应疾病。本文就肠道菌群的分布、种类、影响因素进行大体介绍,主要对肠道菌群与糖脂代谢疾病联系和肠道菌群调节糖脂代谢过程中可能存在的作用机理进行综述,希望能够对糖脂代谢疾病的临床诊治带来裨益,为在此领域上的研究者提供参考价值。
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| 关 键 词： | 肠道菌群，糖脂代谢，糖脂代谢疾病 |
Advance in studying the effect of gut microflora on glycolipid metabolism |
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| YANG Jun,WANG Jian-Yu,CHEN Long,ZHOU Fei,ZENG Zhe-Ling and WEN Xue-Fang.Advance in studying the effect of gut microflora on glycolipid metabolism[J].Microbiology,2019,46(5):1146-1154. |
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| Authors: | YANG Jun WANG Jian-Yu CHEN Long ZHOU Fei ZENG Zhe-Ling and WEN Xue-Fang |
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| Institution: | 1 State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, Jiangxi 330047, China;2 Jiangxi Province Key Laboratory of Edible and Medicinal Resources Exploitation, Nanchang University, Nanchang, Jiangxi 330031, China;3 School of Food Science and Technology, Nanchang University, Nanchang, Jiangxi 330031, China,2 Jiangxi Province Key Laboratory of Edible and Medicinal Resources Exploitation, Nanchang University, Nanchang, Jiangxi 330031, China;4 School of Resource Environmental and Chemical Engineering, Nanchang University, Nanchang, Jiangxi 330031, China,1 State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, Jiangxi 330047, China;3 School of Food Science and Technology, Nanchang University, Nanchang, Jiangxi 330031, China,2 Jiangxi Province Key Laboratory of Edible and Medicinal Resources Exploitation, Nanchang University, Nanchang, Jiangxi 330031, China;4 School of Resource Environmental and Chemical Engineering, Nanchang University, Nanchang, Jiangxi 330031, China,1 State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, Jiangxi 330047, China;2 Jiangxi Province Key Laboratory of Edible and Medicinal Resources Exploitation, Nanchang University, Nanchang, Jiangxi 330031, China;4 School of Resource Environmental and Chemical Engineering, Nanchang University, Nanchang, Jiangxi 330031, China and 1 State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, Jiangxi 330047, China;2 Jiangxi Province Key Laboratory of Edible and Medicinal Resources Exploitation, Nanchang University, Nanchang, Jiangxi 330031, China;4 School of Resource Environmental and Chemical Engineering, Nanchang University, Nanchang, Jiangxi 330031, China |
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| Abstract: | Accumulating literatures indicate that intestinal microflora, known as the second human genome, can affect glycolipid metabolism, and then regulate the corresponding diseases. In this review, we introduce the distribution, species and influencing factors of intestinal microflora. We mainly address the relationship between intestinal microflora and glycolipid metabolic diseases, and the mechanism how intestinal microflora regulates the glycolipid metabolism. Moreover, the potential use of glycolipid metabolism for clinical diagnosis and treatment of diseases is also discussed. |
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| Keywords: | Gut microflora Glycolipid metabolic Glycolipid metabolic disease |
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