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Fluvastatin attenuated ischemia/reperfusion-induced autophagy and apoptosis in cardiomyocytes through down-regulation HMGB1/TLR4 signaling pathway |
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| Authors: | Ding Hua-Sheng Yang Jun Yang Jian Guo Xin Tang Yan-Hong Huang Yan Chen Zhen Fan Zhi-Xing Huang Cong-Xin |
| Affiliation: | 1.Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan University, Wuhan, 430060, People’s Republic of China ;2.Institute of Cardiovascular Diseases, Wuhan University, Wuhan, 430060, People’s Republic of China ;3.Hubei Key Laboratory of Cardiology, Wuhan, 430060, People’s Republic of China ;4.Institute of Cardiovascular Diseases, China Three Gorges University, Yichang, 443000, People’s Republic of China ; |
| Abstract: | Molecular Biology Reports - Fluvastatin, a traditional fat-decreasing drug, is widely used for curing cardiovascular disease. Previous reports demonstrated that fluvastatin pretreatment protected... |
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