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Debio-0932, a second generation oral Hsp90 inhibitor,induces apoptosis in MCF-7 and MDA-MB-231 cell lines |
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| Authors: | Özgür Aykut Kara Altan Gökşen Tosun Nazan Tekin Şaban Gökçe İsa |
| Affiliation: | 1.Department of Veterinary Medicine, Laboratory and Veterinary Health Program, Artova Vocational School, Tokat Gaziosmanpa?a University, Tokat, Turkey ;2.TUBITAK Marmara Research Center, Gene Engineering and Biotechnology Institute, Gebze, Turkey ;3.Department of Biomaterials and Tissue Engineering, Faculty of Engineering and Architecture, Tokat Gaziosmanpa?a University, Tokat, Turkey ;4.Division of Medical Biology, Department of Basic Medical Sciences, Hamidiye Faculty of Medicine, University of Health Sciences, Turkey, Istanbul, Turkey ;5.Experimental Medicine Application & Research Center, Validebag Research Park, University of Health Sciences, Istanbul, Turkey ;6.Department of Genetics and Bioengineering, Faculty of Engineering and Architecture, Tokat Gaziosmanpa?a University, Tokat, Turkey ; |
| Abstract: | Molecular Biology Reports - Heat shock protein 90 (Hsp90) is a key chaperone that is abnormally expressed in cancer cells, and therefore, designing novel compounds to inhibit chaperone activities... |
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| 本文献已被 SpringerLink 等数据库收录！ | |