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| 铝对大鼠纹状体内生长抑素mRNA表达的影响 | |
| 引用本文： | 董大翠,张艳,熊希凯,陈艳贤,朱清华. 铝对大鼠纹状体内生长抑素mRNA表达的影响[J]. 中国组织化学与细胞化学杂志, 1996, 0(4) |
| 作者姓名： | 董大翠 张艳 熊希凯 陈艳贤 朱清华 |
| 作者单位： | 同济医科大学人体解剖学教研室，同济医科大学营养卫生学教研室 |
| 摘 要： | 本实验采用Ｗｉｓｔａｒ大鼠３０只，分为对照组（Ａ组）、硫酸铝钾组（Ｂ组）和硫酸铝钾加柠檬酸组（Ｃ组），分别喂养半年。用原位杂交组织化学和图像分析方法观察大鼠纹状体内生长抑素（Ｓｏｍａｔｏｓｔａｔｉｎ，ＳＳ）ｍＲＮＡ表达的变化。结果表明：给铝组大鼠纹状体内ＳＳｍＲＮＡ表达减少，与对照组的差异有非常显著性意义。 |
| 关 键 词： | 铝生长抑素mRNA，原位杂交，纹状体，大鼠 |
EFFECT OF ALUMINUM ON EXPRESSION OF SOMATOSTATIN mRNA IN THE RAT CORPUS STRIATUM |
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| Dong Dacui, Zhang Yan, Xiong Xikei. EFFECT OF ALUMINUM ON EXPRESSION OF SOMATOSTATIN mRNA IN THE RAT CORPUS STRIATUM[J]. Chinese Journal of Histochemistry and Cytochemistry, 1996, 0(4) | |
| Authors: | Dong Dacui Zhang Yan Xiong Xikei |
| Abstract: | In the present study, 30 wistar rats were divided into three groups. Group A was fornormal control, Group B was fed with a solutio containing aluminum potassium sulfate,Group C fed with a solution containing aluminum postassium sulfate and citric acid. All ofthem were fed 6 month respectively. The level changes of somatostatin mRNA expressed inthe corpus striatum were observed by in site hybridization histochemistry and image analysis. The experimental results showed that the expression level of the SSmRNA in the corpusstriatum of the experimental group significantly decreased as compared with the controlgroup. |
| Keywords: | Aluminum potassium sulfate SSmRNA In situ hybridization Corpusstriatum Rats |
| 本文献已被 CNKI 等数据库收录！ | |