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Limonoids from the fruits of Melia toosendan
Authors:Jin-Feng Hu  Hui Fan  Li-Jun Wang  Shi-Biao Wu  Yun Zhao
Institution:Department of Natural Products for Chemical Genetic Research, Key Laboratory of Brain Functional Genomics, Ministry of Education & Shanghai Key Laboratory of Brain Functional Genomics (MOE & SBFG), East China Normal University, No. 3663 Zhongshan Road N, Shanghai 200062, PR China
Abstract:Four (14) new and seven known limonoids were isolated from the EtOH extract of the fruits of Melia toosendan. The structures of the new compounds were established on the basis of spectroscopic methods to be 12-O-methyl-1-O-deacetylnimbolinin B (1), 12-O-methy-1-O-tigloyl-1-O-deacetylnimbolinin B (2), 12-O-ethylnimbolinin B (3), and 1-O-cinnamoyl-1-O-debenzoylohchinal (4). Additionally, two new tirucallane-type triterpenoids, named meliasenins S (5) and T (6), were obtained from the same fractions during purification of the limonoids.
Keywords:Melia toosendan  Meliaceae  Limonoids  Tirucallane-type triterpenoids
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