Synonymous and Nonsynonymous Substitution Rates in Diatoms: A Comparison Between Chloroplast and Nuclear Genes |
| |
Authors: | Ulf Sorhannus Martin Fox |
| |
Institution: | (1) Department of Biology and Health Services, Edinboro University of Pennsylvania, Edinboro, PA 16444, USA, US |
| |
Abstract: | Rates of synonymous and nonsynonymous nucleotide substitutions and codon usage bias (ENC) were estimated for a number of
nuclear and chloroplast genes in a sample of centric and pennate diatoms. The results suggest that DNA evolution has taken
place, on an average, at a slower rate in the chloroplast genes than in the nuclear genes: a rate variation pattern similar
to that observed in land plants. Synonymous substitution rates in the chloroplast genes show a negative association with the
degree of codon usage bias, suggesting that genes with a higher degree of codon usage bias have evolved at a slower rate.
While this relationship has been shown in both prokaryotes and multicellular eukaryotes, it has not been demonstrated before
in diatoms.
Received: 3 June 1998 / Accepted: 11 August 1998 |
| |
Keywords: | : Diatom — Chloroplast — Nucleus — Protein-coding gene — Nonsynonymous substitution rate — Synonymous substitution rate — Codon usage bias — Divergence time |
本文献已被 SpringerLink 等数据库收录! |
|