Radionuclide-conjugated monoclonal antibodies: a synthesis of immunology,inorganic chemistry and nuclear science |
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| Affiliation: | 1. Metabolism Branch, National Cancer Institute of NIH, Bethesda, MD 20892, USA;2. Radiation Oncology Branch, National Cancer Institute of NIH, Bethesda, MD 20892, USA;3. Argonne National Laboratory, Argonne, IL, USA;1. Helmholtz-Zentrum Dresden-Rossendorf, Institute of Resource Ecology, Dresden, Germany;2. Helmholtz-Zentrum Dresden-Rossendorf, Institute of Resource Ecology, Leipzig, Germany;3. Helmholtz-Zentrum Dresden-Rossendorf, Institute of Ion Beam Physics and Materials Research, Dresden, Germany;4. Bundesanstalt für Geowissenschaften und Rohstoffe, BGR, Germany;1. Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA;2. College of Nuclear Science and Technology, Harbin Engineering University, Harbin 150001, China;3. Dipartimento di Scienze Chimiche, Università di Padova, via Marzolo 1, I-35131 Padova, Italy;1. Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, Nanjing 210023, China;2. Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Jiangsu National Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University (NanjingTech), Nanjing 211816, China;1. Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan;2. Chemistry Division, Directorate of Science, Pakistan Institute of Nuclear Science and Technology (PINSTECH), P.O. Nilore, Islamabad, 45650, Pakistan |
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| Abstract: | Radionuclide-conjugated monoclonal antibodies are new modalities for tumor diagnosis/imaging and therapy. The availability and common usage of these ‘magic bullets’ depends on the biotechnological development and synthesis of three fields of science. |
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