α-Pyrone derivatives from the endolichenic fungus Nectria sp. |
| |
| Institution: | 1. Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany;2. Bio-Pharmaceutical Chemistry and Molecular Pharmacology, Faculty of Applied Natural Sciences, Technische Hochschule Köln, Chempark, 51368 Leverkusen, Germany;3. Institute of Inorganic and Structural Chemistry, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany;4. Department of Biomedical Sciences, Faculty of Human Sciences, University of Osnabrueck, Barbarastrasse 22, 49076 Osnabrück, Germany;5. Institute for Molecular Medicine I, Medical Faculty, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany;6. Institute of Pharmaceutical and Medicinal Chemistry, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany;7. Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China |
| |
| Abstract: | Five new α-pyrone derivatives, necpyrones A–E (1–5), together with seven known compounds (6–12), were isolated from the extract of an endolichenic fungus Nectria sp. Chemical structures of these compounds were elucidated by spectroscopic analyses (HRESIMS and NMR). The absolute configurations of C-6 in the pyrone ring as well as the chiral carbons at the aliphatic side chain resulted from hydroxyl substitute were finally determined on the basis of measurement of ECD and Kusumi–Mosher method. |
| |
| Keywords: | Endophytic fungus Kusumi–Mosher method |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
