Two new triterpene saponins from the roots of Ilex pubescens |
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| Institution: | 1. International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, China;2. Department of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510006, China;1. Department of Pharmacology, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, PR China;2. Guangzhou Institute of Cardiovascular Disease, Guangzhou Key Laboratory of Cardiovascular Disease, and the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, PR China;1. Saskatoon Research Centre, Agriculture and Agri-Food Canada, 107 Science Place, Saskatoon, Saskatchewan, Canada S7N 0X2;2. National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9;1. Key Laboratory of Tobacco Chemistry of Yunnan Province, China Tobacco Yunnan Industrial Co., Ltd, Kunming 650231, PR China;2. School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Nature Products, Kunming Medical University, Kunming 650500, PR China;1. Department of Tibetan Medicine Pharmacology, Shenyang Pharmaceutical University, Shenyang, China;2. Department of Research Center for High Altitude Medicine, Qinghai University, Xining, China;1. School of Pharmaceutical Science, Hainan Medical University, Haikou 571101, China;2. Research Center on Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbin 150076, China;3. Hainan Provincial Institute for Drug and Food Control, Haikou 570216, China;1. Instituto de Desarrollo Tecnológico para la Industria Química (INTEC, UNL-CONICET), Güemes 3450, 3000 Santa Fe, Argentina;2. Facultad Regional Santa Fe, Universidad Tecnológica Nacional, Lavaise 610, 3000 Santa Fe, Argentina;3. Polymer Institute, Slovak Academy of Science, Dúbravská cesta 9, 84541 Bratislava, Slovakia |
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| Abstract: | Two new triterpene saponins, namely, ilexpublesnin S (1) and T (2), and six known saponins were isolated from the roots of Ilex pubescens. The structures of the new compounds were elucidated through extensive spectroscopic methods (IR, HR-ESI-MS, 1D and 2D NMR). Sugar residues obtained after acid hydrolysis were identified through TLC and HPLC. Compound 1 contains a 24-aldehyde group, which is rare for triterpene saponins from Ilex. |
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| Keywords: | Aquifoliaceae Triterpene saponins 24-Aldehyde group |
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