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Pathophysiology of ageing, longevity and age related diseases
Authors:Alexander Bürkle  Graziella Caselli  Claudio Franceschi  Erminia Mariani  Paolo Sansoni  Angela Santoni  Giancarlo Vecchio  Jacek M Witkowski  Calogero Caruso
Affiliation:(1) Department of Biology, University of Konstanz, Box X911, Konstanz, Germany;(2) Department of Demographic Sciences, University "La Sapienza" of Rome, Rome, Italy;(3) Department of Experimental Pathology and CIG – Interdepartmental Center "L. Galvani", University of Bologna, Italy;(4) Immunology and Genetics Laboratory, Institute Codivilla-Putti, Bologna, Italy;(5) Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy;(6) Department of Internal Medicine and Biomedical Sciences, University of Parma, Parma, Italy;(7) Department of Experimental Medicine, University "La Sapienza" of Rome, Rome, Italy;(8) Department of Cellular and Molecular Biology and Pathology, University of Naples Federico II, Naples, Italy;(9) Department of Pathophysiology, Medical University of Gdansk, Gdansk, Poland;(10) Immunosenescence Unit, Department of Pathobiology and Biomedical Methodologies, University of Palermo, Palermo, Italy
Abstract:On April 18, 2007 an international meeting on Pathophysiology of Ageing, Longevity and Age-Related Diseases was held in Palermo, Italy. Several interesting topics on Cancer, Immunosenescence, Age-related inflammatory diseases and longevity were discussed. In this report we summarize the most important issues. However, ageing must be considered an unavoidable end point of the life history of each individual, nevertheless the increasing knowledge on ageing mechanisms, allows envisaging many different strategies to cope with, and delay it. So, a better understanding of pathophysiology of ageing and age-related disease is essential for giving everybody a reasonable chance for living a long and enjoyable final part of the life.
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