The cutting edges in DNA repair,licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice,cut once |
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| Affiliation: | 1. Life Science Division, 1 Cyclotron Road, Berkeley, CA 94720, USA;2. The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA;1. Key Laboratory for Tropic Diseases Control of the Ministry of Education, Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China;2. Teaching Center of Biology Experiment, Guangzhou Medical University, Guangzhou, 511436, China;3. Microbiology Laboratory, Center for Disease Control and Prevention of Guangdong Province, Guangzhou, 511430, China;1. Research Economist, USDA Forest Service Pacific Southwest Research Station, USA;2. Department of Applied Economics, Oregon State University, USA;3. Bren School of Environmental Science & Management, University of California, Santa Barbara, USA;1. The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, 52900 Israel;1. College of Biology, Hunan University, Changsha, 410082, China;2. TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China |
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| Abstract: | |
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| Keywords: | Exonuclease Enzyme–DNA complex Genome maintenance Crystallography Structure-specific nuclease DNase RNase Nucleases DNA RNA Endonucleases Metals Magnesium Zinc Manganese DNA repair Base excision repair Mismatch repair Double strand break repair Nucleotide incision repair Telomere APE1 Nfo EndoIV TDP2 UVDE Vsr Nfi EndoV Mre11 FEN1 Exo1 BER"},{"#name":"keyword","$":{"id":"kw0170"},"$$":[{"#name":"text","_":"base excision repair MMR"},{"#name":"keyword","$":{"id":"kw0180"},"$$":[{"#name":"text","_":"mismatch repair DSBR"},{"#name":"keyword","$":{"id":"kw0190"},"$$":[{"#name":"text","_":"double strand break repair Ss"},{"#name":"keyword","$":{"id":"kw0200"},"$$":[{"#name":"text","_":"single stranded Ds"},{"#name":"keyword","$":{"id":"kw0210"},"$$":[{"#name":"text","_":"double stranded APE1"},{"#name":"keyword","$":{"id":"kw0220"},"$$":[{"#name":"text","_":"apurinic/apyrimidinic endonuclease 1 Nfo"},{"#name":"keyword","$":{"id":"kw0230"},"$$":[{"#name":"text","_":"Endonuclease IV TDP2"},{"#name":"keyword","$":{"id":"kw0240"},"$$":[{"#name":"text","_":"tyrosyl DNA phosphodiesterase 2 UVDE"},{"#name":"keyword","$":{"id":"kw0250"},"$$":[{"#name":"text","_":"UV damage endonuclease Vsr"},{"#name":"keyword","$":{"id":"kw0260"},"$$":[{"#name":"text","_":"very short patch repair endonuclease Nfi"},{"#name":"keyword","$":{"id":"kw0270"},"$$":[{"#name":"text","_":"Endonuclease V Mre11"},{"#name":"keyword","$":{"id":"kw0280"},"$$":[{"#name":"text","_":"meiotic recombination 11 FEN1"},{"#name":"keyword","$":{"id":"kw0290"},"$$":[{"#name":"text","_":"flap endonuclease 1 Exo1"},{"#name":"keyword","$":{"id":"kw0300"},"$$":[{"#name":"text","_":"exonuclease 1 Dcm"},{"#name":"keyword","$":{"id":"kw0310"},"$$":[{"#name":"text","_":"DNA-cytosine methyltransferase 6-4PP"},{"#name":"keyword","$":{"id":"kw0320"},"$$":[{"#name":"text","_":"(6-4) photoproduct or (6,4) pyrimidine-pyrimidones CPD"},{"#name":"keyword","$":{"id":"kw0330"},"$$":[{"#name":"text","_":"cyclobutane pyrimidine dimer NIR"},{"#name":"keyword","$":{"id":"kw0340"},"$$":[{"#name":"text","_":"nucleotide incision repair Lig1"},{"#name":"keyword","$":{"id":"kw0350"},"$$":[{"#name":"text","_":"ligase 1 DBD"},{"#name":"keyword","$":{"id":"kw0360"},"$$":[{"#name":"text","_":"DNA binding domain |
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