Further cycloartane and friedelane triterpenoids from the leaves of Caloncoba glauca |
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| Affiliation: | 1. Laboratory of Natural Products Chemistry, Department of Chemistry, University of Dschang, P.O. Box 67, Dschang, Cameroon;2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People''s Republic of China;3. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People''s Republic of China;1. G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022, Vladivostok, Russian Federation;2. P.P. Shirshov Institute of Oceanology of the Russian Academy of Sciences, Nakhimovsky Pr., 36, 117997, Moscow, Russian Federation;1. Department of Oral Microbiology and Immunology, DRI, and BK21 Plus Program, School of Dentistry, Seoul National University, Seoul, Republic of Korea;3. Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea;2. Radiation Biotechnology Research Division, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Republic of Korea;1. Japan Society for the Promotion of Science, 5-3-1 Kouji-machi, Chiyoda-ku, Tokyo 102-0083, Japan;2. Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, 3435 Main Street, 109 Foster Hall, Buffalo, NY 14214, USA;3. Department of Oral Microbiology, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido 061-0293, Japan |
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| Abstract: | 
Three new triterpenoids, caloncobic acid C (1), caloncobalactone C (2) and glaucalactone B (3) were isolated from the leaves of Caloncoba glauca. Their structures were elucidated on the basis of spectroscopic evidence. These compounds were evaluated for their inhibitory activities against human and mouse 11β-hydroxysteroid dehydrogenase type 1 and type 2. |
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| Keywords: | Cycloartane Friedelane |
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