NIR fluorescent ytterbium compound for in vivo fluorescence molecular imaging |
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| Authors: | Kazuki Aita Takashi Temma Yuji Kuge Koh‐ichi Seki Hideo Saji |
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| Affiliation: | 1. Department of Patho‐Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan;2. Central Institute of Isotope Science, Hokkaido University, Japan;3. Department of Tracer Kinetics and Bioanalysis, Graduate school of Medicine, Hokkaido University, Japan |
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| Abstract: | ![]()
We have developed a new NIR fluorescent probe based on an ytterbium(III) (E)‐1‐(pyridin‐2‐yl‐diazenyl)naphthalen‐2‐ol (PAN) complex. This probe emits near‐infrared luminescence derived from the Yb ion through excitation of the PAN moiety with visible light (λex = 530 nm, λem = 975 nm). The results support the possible utility of the probe for in vivo fluorescence molecular imaging. Copyright © 2009 John Wiley & Sons, Ltd. |
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| Keywords: | ytterbium near‐infrared energy transfer fluorescence |
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