β Propellers: structural rigidity and functional diversity |
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Authors: | Vilmos Fü l p,David T Jones |
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Affiliation: | Department of Biological Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK |
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Abstract: | Recently solved structures and proposed models have helped to reveal the structural characteristics of the β-propeller fold, as well as the features that contribute to its high rigidity and stability. Possible strategies for identifying β-propeller proteins in newly characterised sequences are helping to overcome the problems of predicting the β-propeller fold from amino acid sequences. |
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Keywords: | Protein structure β -propeller fold Structure prediction WD repeats ‘ Velcro’ closure |
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