| 影响主动脉平滑肌细胞迁移的因素 |
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| 引用本文： | 范丽娟,;张燕,;尹苗,;王长法. 影响主动脉平滑肌细胞迁移的因素[J]. 生命科学, 2014, 0(7): 696-702 |
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| 作者姓名： | 范丽娟, 张燕, 尹苗, 王长法 |
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| 作者单位： | [1]山东师范大学生命科学学院,济南250014; [2]山东省农业科学院奶牛研究中心,济南250100 |
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| 基金项目： | 基金项目：山东省中青年科学家科研奖励基金计划项目（BS2011SW049） |
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| 摘 要： | 平滑肌细胞(vascular smooth muscle cell,VSMC)的迁移对血管发育、动脉粥样硬化和术后再狭窄等起到关键性的作用。主要从激发VSMC迁移的关键炎性细胞因子、细胞间相互作用的核心成员、microRNA、细胞骨架和上述各因素的迁移信号通路这几方面来综述VSMC的迁移。
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| 关 键 词： | 血管平滑肌细胞 迁移 影响因素 |
Influencing factors of vascular smooth muscle cell migration |
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| Affiliation: | FAN Li-Juan, ZHANG Yan, YIN Miao, WANG Chang-Fa (1 College of Life Science, Shandong Normal University, Jinan 250014, China; 2 Dairy Cattle Research Center, Shandong Academy of Agricultural Science, Jinan 250100, China) |
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| Abstract: | The migration of vascular smooth muscle cell （VSMC） plays a key role in vascular development, atherogenesis and restenosis. Here, we review recent progresses made toward the key inflammatory cytokines triggerring VSMC migration, key players between cell-matrix and cell-cell contacts, microRNA, cytoskeleton and signaling pathway events of each factor mediating VSMC migration, which are characteristics as influence factors of VSMC migration. |
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| Keywords: | vascular smooth muscle cells migration influencing factor |
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