Protein structure topological comparison, discovery and matching service |
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Authors: | Torrance G M Gilbert D R Michalopoulos I Westhead D W |
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Affiliation: | Bioinformatics Research Centre, Department of Computer Science, University of Glasgow, Glasgow G12 8QQ, UK. |
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Abstract: | We describe a fold level fast protein comparison and motif matching facility based on the TOPS representation of structure. This provides an update to a previous service at the EBI, with a better graph matching with faster results and visualization of both the structures being compared against and the common pattern of each with the target domain. AVAILABILITY: Web service at http://balabio.dcs.gla.ac.uk/tops or via the main TOPS site at http://www.tops.leeds.ac.uk. Software is also available for download from these sites. |
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