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XTandem Parser: An open‐source library to parse and analyse X!Tandem MS/MS search results
Authors:Thilo Muth  Marc Vaudel  Harald Barsnes  Lennart Martens  Albert Sickmann
Institution:1. Leibniz‐Institut für Analytische Wissenschaften ‐ ISAS ‐ e.V. – Institute for Analytical Sciences, Dortmund, Germany;2. Lehrstuhl für Bioinformatik, Institut für Informatik, Friedrich‐Schiller‐Universit?t Jena, Germany;3. Department of Informatics, University of Bergen, Bergen, Norway
Abstract:Identification of proteins by MS plays an important role in proteomics. A crucial step concerns the identification of peptides from MS/MS spectra. The X!Tandem Project ( http://www.thegpm.org/tandem ) supplies an open‐source search engine for this purpose. In this study, we present an open‐source Java library called XTandem Parser that parses X!Tandem XML result files into an easily accessible and fully functional object model ( http://xtandem‐parser.googlecode.com ). In addition, a graphical user interface is provided that functions as a usage example and an end‐user visualization tool.
Keywords:Bioinformatics  Protein identification  X!Tandem
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