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A binding free energy decomposition approach for accurate calculations of the fidelity of DNA polymerases
Authors:Robert Rucker  Peter Oelschlaeger  Arieh Warshel
Institution:1. Department of Chemistry, University of Southern California, Los Angeles, California;2. Chemistry Department and Center for Macromolecular Modeling and Materials Design, California State Polytechnic University, Pomona, California
Abstract:
Keywords:DNA polymerase  replication fidelity  enzyme catalysis  metalloenzyme  free energy
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