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广西梧州市鼻咽癌现场10年的前瞻性研究
引用本文:邓洪,曾毅.广西梧州市鼻咽癌现场10年的前瞻性研究[J].病毒学报,1992,8(1):32-37.
作者姓名:邓洪  曾毅
作者单位:广西梧州市肿瘤研究所 (邓洪,黄乃琴,黄玉英,黎跃,苏辉民,钟汉桑,练英熙),中国预防医学科学院病毒学研究所 (曾毅),广西自治区人民医院 (王培中),法国巴斯德研究(G.de The)
摘    要:

关 键 词:E-B病毒  鼻咽肿瘤  前瞻性研究

PROSPECTIVE STUDIES OF NASOPHARYNGEAL CARCINOMA FOR 10 YEARS IN WUZHOU CITY,GUANGXI
Deng Hong Zeng Yi Huang Naiqin Huang Yuying Li Yue Su Luimin Zhong Hanxin Lian Yingxi Wang Peizhong G.de The l.Cancer Unit of Wuzhou City,Guangxi.PROSPECTIVE STUDIES OF NASOPHARYNGEAL CARCINOMA FOR 10 YEARS IN WUZHOU CITY,GUANGXI[J].Chinese Journal of Virology,1992,8(1):32-37.
Authors:Deng Hong Zeng Yi Huang Naiqin Huang Yuying Li Yue Su Luimin Zhong Hanxin Lian Yingxi Wang Peizhong Gde The lCancer Unit of Wuzhou City  Guangxi
Institution:Deng Hong Zeng Yi Huang Naiqin Huang Yuying Li Yue Su Luimin Zhong Hanxin Lian Yingxi Wang Peizhong G.de The l.Cancer Unit of Wuzhou City,Guangxi2.Institute of Virology,Chinese Academy of Preventive Medicine,Beijing3.Guangxi Autonomous Regional Hospital,Nanning,Guangxi4.Institute Pasteur,Paris,France
Abstract:A serological mass survey of NPC was carried out in Wuzhou city, Guangxi. 1,136 out of 20,726 persons of age over 40 had Epstein-Barr viral IgA/VCA antibody. Among them 18 patients were diagnosed just after serological screening.The IgA/VCA positive-persons were followed up yearly for 10 years. The early detection rate for NPC increased from 25.8% to 87.2%. NPC could be detected up to 10th year. Therefore, NPC can be predicted 5-10 years before diagnosis of NPC was made.Altogether 57 NPC patient ( 93% ) were detected from the IgA/VCA antibody positive group, while only 4( 7% )from the antibody negative group. The NPC detection rate of NPC in these two groups was 4665.5 /100,000 and 20.4/100,000 respectively. All these data indicate that Eps tein-Barr virus plays an important role in the development of NPC.
Keywords:Epstein-Barr virus Nasopharyngeal carcinoma Serological screening Prospective studies  
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