Characteristics of extracellular protein production by a plasmidless derivative of Staphylococcus simulans biovar staphylolyticus |
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| Authors: | James D. Nitterauer Harry E. Heath Lucie S. Heath Paul A. LeBlanc Gary L. Sloan |
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| Affiliation: | Department of Microbiology, University of Alabama, Tuscaloosa 35487. |
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| Abstract: | A derivative of Staphylococcus simulans biovar staphylolyticus cured of all five plasmids present in the wild-type organism was developed, and the characteristics of extracellular protein production by this plasmidless strain were compared to those of the wild type. Although staphylolytic endopeptidase (lysostaphin) and beta-lactamase are known to be plasmid encoded, analysis of this cured strain revealed that most other extracellular proteins are chromosomally encoded. |
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| Keywords: | Staphylococcus simulans biovar staphylolyticus Extracellular protein Plasmid cured |
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