Affinity of Ionic Species of Nucleoside Transport Protein Inhibitors |
| |
| Authors: | AH Voorschuur Ap Ijzerman |
| |
| Institution: | Div. of Medicinal Chemistry, Center for Bio-Pharmaceutical Sciences , POB 9502, 2300, RA Leiden, The Netherlands |
| |
| Abstract: | Abstract A class of very potent nucleoside transport inhibitors is present in two molecular forms around physiological pH. We investigated whether the monoprotonated or the unionized species of these molecules binds to this camer protein with higher affinity. |
| |
| Keywords: | |
|
|
