Synthese d'Oligodesoxyribonucleotides sur Support de Gel de Silice par la Methode au Phosphotriester |
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| Authors: | J Ben Hattar B Rayner J-L Imbach |
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| Institution: | Laboratoire de Chimie Bio-Organique , ERA n° 948 du CNRS Université des Sciences et Techniques du Languedoc , Place Eugène-Bataillon, 34060 Montpellier Cedex, France |
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| Abstract: | Abstract A method of oligonucleotide synthesis was developped on a silica gel support by the phosphotriester approach. Using this method, the nonanucleoside octaphosphate dT(pT)8 was synthetized in 28% yield. |
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| Keywords: | 5′-Nucleotidase Fludarabine cN-II HPLC NMR Resistance |
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