The Synthesis of Branched Oligonucleotides as Signal Amplification Multimers for Use in Nucleic Acid Assays |
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| Authors: | Thomas Horn Brian D. Warner Joyce A. Running Kristi Downing Jennifer Clyne Mickey S. Urdea |
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| Affiliation: | Chiron Corporation , 4560 Horton Street, Emeryville, California, 94608 |
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| Abstract: | ![]()
Abstract Branched oligonucleotides have been synthesized using phosphoramidite derivatives with two protected hydroxyl functions. These molecules are employed for a label amplification strategy used in DNA probe diagnostics. |
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