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Low Level,Detection of Modified DNA Bases and Nucleosides by FAB MS/MS
Authors:E. De Pauw  E. Marafante  J. Riego  C. Leuratti
Affiliation:Commission of the European Comrrunities, Joint Research Centre, Radiochemistry Division, Environment Institute , 21020, ISPRA (VA), Italy
Abstract:
Abstract

The identification and quantitation of DNA adducts formed by reaction of genotoxic chemicals with DNA may provide direct evidence of exposure t o mutagens and carcinogens and may make possible a beginning of risk estimation based on Molecular Dosimetry approach.
Keywords:
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