Low Level,Detection of Modified DNA Bases and Nucleosides by FAB MS/MS |
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Authors: | E. De Pauw E. Marafante J. Riego C. Leuratti |
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Affiliation: | Commission of the European Comrrunities, Joint Research Centre, Radiochemistry Division, Environment Institute , 21020, ISPRA (VA), Italy |
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Abstract: | Abstract The identification and quantitation of DNA adducts formed by reaction of genotoxic chemicals with DNA may provide direct evidence of exposure t o mutagens and carcinogens and may make possible a beginning of risk estimation based on Molecular Dosimetry approach. |
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