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DNA Apurinic Sites: Synthesis of a Model Compound and Study of its Reactivity with 3-Aminocarbazole |
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| Authors: | J-J Vasseur B Rayner J-L Imbach S Verla J A McCloskey J W Lown |
| Institution: | 1. Universite des Sciences et Techniques du Languedoc, Laboratoire de Chimie Bio-Organique , Place Eugene Bataillon, 34060, Montpellier Cédex, France;2. Departments of Medicinal Chemistry and Biochemistry , University of Utah , Salt Lake City, Utah, 84112, USA;3. Department of Chemistry , University of Alberta , Edmonton, Alberta, T6G 2G2, Canada |
| Abstract: | Abstract The mechanism of breakage of apurinic DNA with 3-aminocarbazole was determinated on a short oligonucleotide model. The results founded contrast with those reported in the literature.1 |
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