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Coccidioides immitis endospores: Phagocytosis by human cells
Authors:S C Deresinski  H B Levine  D A Stevens
Institution:(1) Department of Medicine, University of South Florida Medical School, Tampa, Florida;(2) U.S. Naval Biomedical Research Laboratory, Oakland, California;(3) Santa Clara Valley Medical Center and the Institute for Medical Research, San Jose, California;(4) Stanford University, Stanford, California
Abstract:Phagocytosis of killed endospores by glass adherent peripheral human mononuclear cells was studied. Phagocytosis continued through 30 minutes of incubation. No difference in rates of ingestion could be detected when cells from coccidioidin-reactive and nonreactive subjects were compared although both groups ingested endospores more avidly than latex particles.
Keywords:Phagocytosis  Coccidioides immitis  Endospores  Coccidioidomycosis  Mononuclear leukocytes  Cellular immunity
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