Studies of the possibility that RNA polymerase participates in mutagenesis in bacteriophage T4 |
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| Authors: | S I Alikhanian E S Piruzian N G Yaroslavtseva |
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| Affiliation: | Institute of Genetics and Selection of Industrial Microorganisms, Moscow U.S.S.R. |
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| Abstract: | An increased rate of mutagenesis of phage T4 by base analogues was observed in Escherichia coli strains resistant to both rifampicin and streptolydigin and shown to have defective RNA polymerase. The results suggest that RNA polymerase may be involved in the production of mutations by errors of replication. |
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| Keywords: | AP BUdR 5-bromodeoxyuridine TCA trichloracetic acid |
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