| Abstract: | Two-dimensional electrophoresis of ribosomal proteins makes it possible to evaluate the phylogenic distance between any set of two species. The evaluation is based on the number of spots having the same electrophoretic mobility in the two species. The two-dimensional finger-prints of ribosomal proteins from mammals, reptiles and birds, which have diverged 300 million years ago, are identical. For more remote species with respect to mammals, the number of comigrating spots gradually decreases. For as remote species from mammals as plants, one third of the spots have still the same mobility. Only five proteins from E. coli comigrate with ribosomal protein from mammals. The low evolution of ribosomal proteins indicate the high degree of internal organization of the ribosome. |
