Production of artemisinin by hairy rot cultures of Artemisia annua L in bioreactor |
| |
| Authors: | CZ Liu YC Wang F Ouyang HC Ye GF Li |
| |
| Institution: | (1) State Key Laboratory of Biochemical Engineering , Institute of Chemical Metallurgy, Chinese Academy of Sciences, Beijing, 100080, China;(2) Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China |
| |
| Abstract: | Hairy root cultures of Artemisia annua L were cultivated in four different culture systems: a flask, a bubble column, a modified bubble column and a modified inner-loop airlift bioreactor. The artemisinin contents of hairy root cultures in the bubble column and the modified inner-loop airlift bioreactor were higher than that in the modified bubble column. The growth rate and hairy root distribution in the modified inner-loop airlift bioreactor were better than those in other bioreactors, and dry weight and artemisinin production reached to 26.8 g/L and 536 mg/L after 20 days. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
