| 昆虫表达系统及其在基因工程抗体中的应用 |
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| 引用本文： | 尹长城,刘晶,黄华梁.昆虫表达系统及其在基因工程抗体中的应用[J].中国生物工程杂志,2001,21(3):66-70. |
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| 作者姓名： | 尹长城 刘晶 黄华梁 |
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| 作者单位： | 1. 中国科学院遗传研究所 北京 100101;
2. 中国协和医科大学中国医学科学院医学生物学研究所 昆明650118 |
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| 摘 要： | 昆虫表达系统是一类应用广泛的真核表达系统,该系统具有与其他高等真核表达系统相似的翻译后修饰、加工及转移外源蛋白的能力。本文介绍了昆虫表达系统的构建过程,并以基因工程抗体为主讨论了外源蛋白在昆虫表达体系中的表达特征。
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| 关 键 词： | 抗体工程 昆虫 表达系统 |
Insect Expression Systems and Their Application in Antibody Engineering |
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| Yin Chang\|cheng\ Liu Jing\ Huang Huang\|liang.Insect Expression Systems and Their Application in Antibody Engineering[J].China Biotechnology,2001,21(3):66-70. |
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| Authors: | Yin Chang\|cheng\ Liu Jing\ Huang Huang\|liang |
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| Institution: | Yin Chang\|cheng1\ Liu Jing2\ Huang Huang\|liang1 |
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| Abstract: | Insect expression systems are wide using eukaryotic expression systems and have almost the same post\|translational modification, post\|processing and glycosylation pathways as other higher eukaryote. Here we introduced the construction of recombinant Baculovirus expression system and another novel stable transformation based expression system. Properties of proteins mainly engineering antibodies expressed with insect system were also discussed in this review. |
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| Keywords: | Antibody engineering Insect Expression system |
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