Molecular mechanisms of hormonal activity. I. receptors. neuromediators. systems with second messengers |
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| Authors: | V.?I.?Kulinsky mailto:kulinsky@pp.irkutsk.ru" title=" kulinsky@pp.irkutsk.ru" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,L.?S.?Kolesnichenko |
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| Affiliation: | (1) Department of Biochemistry, Irkutsk State Medical University, ul. Krasnogo Vosstaniya 1, 664003 Irkutsk, Russia;(2) Irkutsk State Medical University, ul. Krasnogo Vosstaniya 1, 664003 Irkutsk, Russia |
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| Abstract: | ![]()
Hormone signal transfer along all of the cell compartments including nucleus is powered by signal transduction systems. Characteristics and importance of hormone receptors, principal components, functional mechanisms, and biological role of different systems with second messengers are described. Considerable examples of the importance of these systems for medicine are adduced. The drugs modifying these systems comprise more than 65% of contemporary medicines.Translated from Biokhimiya, Vol. 70, No. 1, 2005, pp. 33–50.Original Russian Text Copyright © 2005 by Kulinsky, Kolesnichenko. |
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| Keywords: | mechanism of hormone action signal transduction system receptor second messenger protein kinase |
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