Interstrand photocrosslinking of DNA via p-carbamoylvinyl phenol nucleoside |
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| Authors: | Yoshimura Yoshinaga Ito Yoshiaki Fujimoto Kenzo |
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| Affiliation: | PRESTO, Japan Science and Technology Agency, Ishikawa 923-1292, Japan. yosinaga@jaist.ac.jp |
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| Abstract: | 
We report a novel interstrand photocrosslinking of oligodeoxynucleotides (ODNs). In this system, a modified ODN containing p-carbamoylvinyl phenol nucleoside reacts by photoirradiation at 366 nm with adenine residue of a complementary template ODN to yield a crosslinked ODN in 97% yield. |
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