Schistosoma mansoni: Cercarial degradation of a radioactively labeled collagen gel |
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| Authors: | James H McKerrow Kathleen H Jeong |
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| Institution: | Department of Pathology and Department of Epidemiology and International Health, University of California, San Francisco, California 94143, U.S.A. |
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| Abstract: | The apparent penetration activity of Schistosoma mansoni cercariae was quantified by means of an in vitro assay with a radioactively labeled Type I collagen gel. Both live cercariae and cercarial preacetabular gland secretions degraded the collagen. The addition of skin lipid or linoleic acid to the gel surface enhanced the degradation by live cercariae. |
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| Keywords: | Trematode Blood fluke Cercariae Penetration activity Collagen Type I degradation Lipid stimulant |
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