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Interferometric optical fiber sensor for optoacoustic endomicroscopy
Authors:Okan Ülgen  Rami Shnaiderman  Christian Zakian  Vasilis Ntziachristos
Institution:1. Chair of Biological Imaging at the 2. Central Institute for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany;3. Central Institute for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany

Institute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, Germany

Abstract:Optical fiber sensors can offer robust and miniaturized detection of wideband ultrasound, yielding high sensitivity and immunity to electromagnetic interference. However, the lack of cost-effective manufacturing methods prevents the disseminated use of these sensors in biomedical applications. In this study, we developed and optimized a simple method to create optical cavities with high-quality mirrors for acoustic sensing based on micro-manipulation of UV-curable optical adhesives and electroless chemical silver deposition. This approach enables the manufacturing of ultrasound sensors based on Fabry-Pérot interferometers on optical fiber tips with minimal production costs. Characterization and high-resolution optoacoustic imaging experiments show that the manufacturing process yielded a fiber sensor with a small NEP (urn:x-wiley:1864063X:media:jbio202000501:jbio202000501-math-0001) over a broad detection bandwidth (25 MHz), generally outperforming conventional piezoelectric based transducers. We discuss how the new manufacturing process leads to a high-performance acoustic detector that, due to low cost, can be used as a disposable sensor.image
Keywords:endomicroscopy  Fabry-Pérot interferometer  optical fiber sensor  optical resonator  optoacoustic imaging  ultrasound transducer
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