Bioactive phenolic compounds from a medicinal lichen, Usnea longissima |
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| Authors: | Choudhary Muhammad I Azizuddin Jalil Saima Atta-ur-Rahman |
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| Affiliation: | H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi 75270, Pakistan. hej@cyber.net.pk |
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| Abstract: | Natural products, longissiminone A (1) and longissiminone B (2), were isolated along with a known compound, glutinol (3), from a medicinal lichen, Usnea longissima. The structures of compounds 1 and 2 were determined with the help of spectroscopic studies. Compound 1 was found to possess potent anti-inflammatory activity in a cell-based contemporary assay. Cytotoxicity activity measured by cell viability assay showed 100% viability in the presence of 200 microg/mL conc. of these compounds. |
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| Keywords: | Usnea longissima Lichen Usneaceae Glutinol Longissiminone Anti-inflammatory Cytotoxicity |
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