Combining functional and linkage disequilibrium information in the selection of tag SNPs |
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| Authors: | Sham P C Ao S I Kwan J S H Kao P Cheung F Fong P Y Ng M K |
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| Affiliation: | Department of Psychiatry, Institute of Psychiatry, King's College London, UK. |
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| Abstract: | We have developed an online program, WCLUSTAG, for tag SNP selection that allows the user to specify variable tagging thresholds for different SNPs. Tag SNPs are selected such that a SNP with user-specified tagging threshold C will have a minimum R2 of C with at least one tag SNP. This flexible feature is useful for researchers who wish to prioritize genomic regions or SNPs in an association study. AVAILABILITY: The online WCLUSTAG program is available at http://bioinfo.hku.hk/wclustag/ |
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