| 精卵质膜融合过程中卵膜上的候选分子 |
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| 引用本文： | 许媛媛,吴艳红,李秋艳,李云龙. 精卵质膜融合过程中卵膜上的候选分子[J]. 细胞生物学杂志, 2006, 28(1): 33-36 |
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| 作者姓名： | 许媛媛 吴艳红 李秋艳 李云龙 |
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| 作者单位： | 山东师范大学生命科学学院动物抗性实验室 济南250014 |
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| 摘 要： | 受精过程中精卵质膜融合分子机制的研究一直备受关注。随着基因剔除技术的发展及众多新技术的应用,人们发现这一过程涉及多种分子,目前对卵膜上的CD9、糖基化磷脂酰肌醇锚定蛋白和整合素研究较多。现从细胞层次和分子层次上总结三者在精卵质膜融合方面的实验及结论,分析各个实验结果矛盾之处,讨论精卵质膜融合研究的前景。
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| 关 键 词： | 精卵质膜融合 CD9 糖基化磷脂酰肌醇锚定蛋白 整合素 |
| 收稿时间： | 2005-06-10 |
| 修稿时间： | 2005-07-28 |
Candidate Molecules Involved in the Sperm-oocyte Plasema Membrane Fusion on Oocyte Surface |
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| Yuan-Yuan Xu,Yan-Hong Wu,Qiu-Yan Li,Yun-Long Li. Candidate Molecules Involved in the Sperm-oocyte Plasema Membrane Fusion on Oocyte Surface[J]. Chinese Journal of Cell Biology, 2006, 28(1): 33-36 |
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| Authors: | Yuan-Yuan Xu Yan-Hong Wu Qiu-Yan Li Yun-Long Li |
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| Affiliation: | Key Laboratory of Animal Resistantance, College of Life Sciences, Shandong Normal University, Jinan 250014, China |
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| Abstract: | The molecular mechanism of the sperm-oocyte plasma membrane fusion during fertilization has been investigated in recent years. Development of gene targeting and application of new technologies allow us to identify the molecules involved in fertilization processes. Recent studies are focusing on CD9, Glycosylphosphati- dylinositol-anchored proteins and integrins on oocyte surface. This paper summarizes the results and the related experiments on these three moleculesat at celluar and molecular levels. |
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| Keywords: | sperm-oocyte plasema membrane fusion CD9 glycosylphosphatidylinositol-anchored proteins integrin |
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