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Water-borne outbreak of serous meningitis caused by Echovirus-30 in Belarus
Authors:Amvros'eva T V  Titov L P  Malders M  Hovi T  D'iakonova O V  Votiakov V I  Kvacheva Z B  Eremin V F  Sharko R M  Orlova S V  Kazinets O N  Bogush Z F
Institution:Research Institute of Epidemiology and Microbiology, Minsk, Belarus.
Abstract:In recent years outbreak of enterovirus infections caused by Echovirus-30 were rather frequently registered in different European countries. A major outbreak caused by this virus took place during the summer-autumn period of 1997 in the city of Gomel, Belarus. Sanitary epidemiological and molecular epidemiological studies made it possible to determine that the outbreak was water-borne. The sequence analysis of Echovirus-30 strains isolated from water and the cerebrospinal fluid of patients revealed a minor divergence between them (0.2%) indicative of their practical identity. The comparison of the Belorussian isolates with the strains isolated in Europe in 1994-1998 also showed a small percentage of differences in their genomes, which showed that the outbreak of Echovirus-30 infection was probably brought to Belarus from the territories of European countries.
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