SCAR DNA family is enriched in evolutionarily conserved sequences |
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| Authors: | M. V. Penkina O. I. Karpova N. V. Zakharevich T. V. Sizova Yu. F. Bogdanov |
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| Affiliation: | (1) Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia;(2) Moscow State University, Moscow, 119992, Russia |
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| Abstract: | The family of DNA sequences tightly associated with the synaptonemal complex (SC), or SCAR DNA family, has earlier been described as a specific family of golden hamster genomic DNA sequences. DNA sequences similar to golden hamster SCAR DNA proved to be widespread in the genomes of some vertebrates. A comparison with a sample of random sequences showed that the SCAR DNA family is enriched in evolutionarily conserved sequences, which correlates with the universal SC morphology and processes occurring in meiotic prophase I. |
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| Keywords: | meiosis synaptonemal complex SCAR DNA evolutionary conservation |
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