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The Novel Orally Active Proteasome Inhibitor K-7174 Exerts Anti-myeloma Activity in Vitro and in Vivo by Down-regulating the Expression of Class I Histone Deacetylases |
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| Authors: | Jiro Kikuchi Satoshi Yamada Daisuke Koyama Taeko Wada Masaharu Nobuyoshi Tohru Izumi Miyuki Akutsu Yasuhiko Kano Yusuke Furukawa |
| Affiliation: | From the ‡Division of Stem Cell Regulation, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Tochigi 329-0498 and ;the §Division of Hematology, Tochigi Cancer Center, Utsunomiya, Tochigi 320-0834, Japan |
| Abstract: | |
| Keywords: | Cancer Drug Resistance Histone Deacetylase Histone Deacetylase Inhibitors Multiple Myeloma Proteasome |