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Regulatory and developmental aspects of ecdysone-regulated gene expression |
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| Authors: | WILLIAM A. SEGRAVES GEOFF RICHARDS |
| Affiliation: | 1. Howard Hughes Medical Institute, Salk Institute for Biological Studies , 10010 N, Torrey Pines Rd, La Jolla, Ca., 92037, USA Phone: 619 453-4100 ext. 301 Fax: 619 453-4100 ext. 301;2. Laboratoire de Génétique Moléculaire des Eucaryotes du CNRS, Unité 184 de Biologie Moléculaire et de Géni Génétique de l'INSERM , Institut de Chimie Biologique, Faculté de Médecine , 11 rue Humann, 67085, Strasbourg Cedex, France Phone: 33 88 37 12 55 ext. 392 Fax: 33 88 37 12 55 ext. 392 |
| Abstract: | Summary The IXth Ecdysone Workshop marked a turning point in studies of ecdysone and gene regulation, as there has been significant progress in our understanding both of the regulatio9n and function of ecdysone-inducible genes. A number of reports confirmed the existence of molecules bearing structural similarities to vertebrate hormone receptors and regulatory sequences resembling their response elements. Work in progress shows that certain early ecdysone responsive genes may encode transcription factors that interact so as to control subsequent stage and tissue patterns of hormonal response. |
| Keywords: | ecdysone receptors response elements Drosophila chromosome puffs |