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Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors |
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| Authors: | Xuwang Chen Xin Liu Qing Meng Ding Wang Huiqing Liu Erik De Clercq Christophe Pannecouque Jan Balzarini Xinyong Liu |
| Affiliation: | 1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44, West Culture Road, 250012 Ji’nan, Shandong, PR China;2. Institute of Pharmacology, School of Medicine, Shandong University, 44, West Culture Road, 250012 Ji’nan, Shandong, PR China;3. Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium |
| Abstract: | |
| Keywords: | HIV-1 NNRTIs DAPY Piperidin-4-yl-aminopyrimidines Dual conformations Molecular hybridization |
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