Membrane glycopeptides from old and young human erythrocytes (Short Communication) |
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Authors: | Cesare Balduini Carlo Luigi Balduini Edoardo Ascari |
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Affiliation: | Institute of Biological Chemistry, Faculty of Sciences, and Institute of Clinical Medicine, Faculty of Medicine and Surgery, University of Pavia, 27100 Pavia, Italy |
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Abstract: | Glycopeptides were extracted by papain digestion from old and young human erythrocyte membranes and fractionated on DEAE-Sephadex A-25. Chemical characterization of the unfractionated samples and of the main peak eluted from the column indicates that glycoproteins of the erythrocyte membrane undergo significant decreases in sialic acid and galactosamine content with aging. |
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